Drug intelligence / Profile preview

aspirin + clopidogrel + statin + enoxaparin + streptokinase

Development stage
Unknown
Lead developer
Bayer
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral, Intravenous, Subcutaneous
01

Overview

This is a combination therapy consisting of five pharmacological agents commonly used in the acute management of acute coronary syndromes (ACS), particularly ST-elevation myocardial infarction (STEMI). The regimen includes: - **Aspirin** (an antiplatelet agent that irreversibly inhibits cyclooxygenase-1, reducing thromboxane A2 and platelet aggregation) - **Clopidogrel** (a P2Y12 receptor antagonist that inhibits ADP-mediated platelet activation and aggregation) - **Statin** (HMG-CoA reductase inhibitor, lowers cholesterol and stabilizes atherosclerotic plaques) - **Enoxaparin** (a low molecular weight heparin anticoagulant that potentiates antithrombin III to inhibit factor Xa)[1][6] - **Streptokinase** (a fibrinolytic agent that activates plasminogen to dissolve clots) This combination targets multiple pathways involved in thrombosis, inflammation, and plaque stabilization. It is typically used as part of guideline-directed medical therapy for patients with STEMI or high-risk ACS.

Other names
aspirin, clopidogrel, statin, enoxaparin, streptokinase-University of Colombo-Acute Coronary Syndrome-Unstable Angina-Non ST Elevation Myocardial InfarctionACSSLAP regimen
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)F10 (Factor Xa)PLG (Plasminogen)P2Y12 (Purinergic P2Y12 receptor)ATIII (Antithrombin III)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

Beyond the preview

Go deeper on aspirin + clopidogrel + statin + enoxaparin + streptokinase.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on aspirin + clopidogrel + statin + enoxaparin + streptokinase.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call