Drug intelligence / Profile preview

astaxanthin + tocotrienol + zinc

Development stage
Preclinical
Lead developer
Astamed
Modality
Small Molecules
Administration
Oral
01

Overview

**Astaxanthin + tocotrienol + zinc** is a dietary supplement formulation containing 12 mg astaxanthin, 10 mg tocotrienol (a form of vitamin E), and 6 mg zinc per daily dose[1][4]. This combination is designed to provide synergistic antioxidant and anti-inflammatory effects. Astaxanthin is a potent carotenoid antioxidant derived from microalgae, tocotrienol enhances lipid-based antioxidative activity and supports astaxanthin's effects, while zinc stabilizes antioxidant enzyme activity (notably SOD1). This formulation has been tested in elderly subjects in clinical trials and demonstrated significant improvements in muscle strength, endurance, and muscle cross-sectional area when paired with exercise. The supplement targets oxidative stress and inflammation, which can contribute to age-related muscle decline, mobility loss, and reduced endurance[1][4]. Mechanistically, astaxanthin acts at cellular membranes to scavenge ROS, tocotrienol counteracts lipid peroxidation and modulates antioxidative pathways, while zinc is a cofactor for numerous antioxidant enzymes and supports immunological and healing processes[1][2]. Primary indications studied: improving muscle strength, endurance, mobility, and potentially age-related sarcopenia and dynapenia[1]. Developer: Astamed

Brand names
Astamed
Other names
AX formulation
02

Targets

NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)Misfolded SOD1Ferroptosis (Ferroptosis regulators)

Beyond the preview

Go deeper on astaxanthin + tocotrienol + zinc.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on astaxanthin + tocotrienol + zinc.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call