astaxanthin-rich Phaffia rhodozyma extract

Astaxanthin-rich Phaffia rhodozyma extract is derived from the yeast *Phaffia rhodozyma* (now known as *Xanthophyllomyces dendrorhous*), a significant natural source of the potent antioxidant carotenoid, astaxanthin. [7, 8] Astaxanthin is the primary active component, making up approximately 80% of the total carotenoid content in the yeast. [6] The extract is utilized as a nutraceutical and dietary supplement for human consumption, and as a feed additive in aquaculture to pigment the flesh of farmed salmon and trout. [6, 7, 12, 18] The primary mechanism of action is its powerful antioxidant property, where astaxanthin neutralizes free radicals and reactive oxygen species, protecting cells from oxidative damage. [1, 2, 4, 5] Research has explored its anti-inflammatory, immune-modulating, and anti-cancer properties. [1, 2, 5] A preclinical study in a rat model of benign prostatic hyperplasia (BPH) showed the extract inhibited BPH development at a level comparable to finasteride, suggesting it could be a potential alternative therapy. [10, 13, 15] However, in a separate study on a rat model of prostate cancer, the extract did not show any chemopreventive activity.

Brand names

AstaFermAQUASTARed Star Phaffia Natural ColorEcotone Phaffia natural color

Other names

Phaffia yeast extractXanthophyllomyces dendrorhous extract