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AT19 is a universal chimeric antigen receptor T cell (CAR-T) therapy developed by Ucello Therapeutics. It is designed to target CD19, a protein expressed on the surface of B cells. The drug functions as a CD19 inhibitor and is intended for the treatment of hematological malignancies that express CD19, such as B-cell lymphoma and CD19-positive acute lymphoblastic leukemia. As a universal CAR-T product, it aims to provide an off-the-shelf cellular immunotherapy option for patients with relapsed or refractory blood cancers[1].
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