Drug intelligence / Profile preview

atazanavir

Development stage
Approved
Lead developer
Bristol Myers Squibb
Modality
Small Molecules
Administration
Oral
01

Overview

Atazanavir is an antiretroviral drug of the protease inhibitor class used in combination with other antiretrovirals for the treatment of human immunodeficiency virus (HIV) infection in adults and children. It works by binding to and inhibiting HIV-1 protease, an enzyme required for the cleavage of viral polyprotein precursors into functional proteins, thereby preventing the formation of mature infectious viral particles. Atazanavir is distinguished from other protease inhibitors by its once-daily dosing and a more favorable lipid profile. It was developed by Bristol Myers Squibb and approved by the FDA in 2003[1][2][7].

Brand names
ReyatazEvotaz
Other names
ATV
02

Targets

PR (Progesterone receptor)

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