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ATB-720

Development stage: Preclinical
Lead developer: Autotelic Bio
Modality: Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics

Overview

ATB-720 is an antisense oligonucleotide (ASO) therapeutic candidate under development by Autotelic Bio. It is characterized as a first-in-class immune modulator designed for the treatment of inflammatory dermatological conditions, specifically atopic dermatitis and psoriasis. Currently in the discovery stage, ATB-720 utilizes RNA-targeting technology to modulate immune pathways associated with the pathogenesis of these skin diseases. As an RNA-based therapy, it aims to provide a targeted approach to immune regulation, though its specific molecular target has not been publicly disclosed by the developer.

Targets

CHI3L1 (Chitinase-3-like protein 1)

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