Drug intelligence / Profile preview

Atenas

Development stage
Discontinued
Lead developer
EMS
Modality
Small Molecules
Administration
Oral
01

Overview

**Atenas** is an oral fixed-dose combination product being developed by **EMS** for patients with **type 2 diabetes mellitus and hypertension**. Public trial records identify Atenas as the combination of **empagliflozin, telmisartan, and amlodipine** in a Phase III randomized, double-blind, triple-dummy study. Mechanistically, it combines an **SGLT2 inhibitor** to lower glucose via increased urinary glucose excretion with an **angiotensin II type 1 receptor blocker** and a **dihydropyridine calcium channel blocker** to reduce blood pressure. The asset appears to be positioned as a single-pill oral cardiometabolic combination intended for patients who require treatment of both hyperglycemia and hypertension.

Brand names
Atenas
Other names
Atenasempagliflozin + telmisartan + amlodipine
02

Targets

AGTR1 (Angiotensin II Type-1 receptor)SGLT2 (Sodium-glucose cotransporter protein subunit 2)CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)

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