atenolol

Atenolol is a selective β1-adrenergic receptor antagonist (beta-blocker) primarily used to treat cardiovascular diseases such as hypertension, angina pectoris, and myocardial infarction. Developed in 1976 as a replacement for propranolol, it reduces cardiac activity by blocking β1 receptors in the heart, leading to decreased heart rate and contractility. Unlike propranolol, atenolol does not cross the blood-brain barrier significantly, minimizing central nervous system side effects. It is also used for arrhythmias and can be administered orally or intravenously[1][2][4][5]. Its mechanism of action involves reducing myocardial oxygen demand and stabilizing cardiac rhythm[6].

Brand names

Tenormin天诺敏

Other names

阿替洛尔氨酰心安