Drug intelligence / Profile preview

atomoxetine + coenzyme Q10

Development stage
Phase 3
Lead developer
Eli Lilly
Modality
Small Molecules
Administration
Oral
01

Overview

A combination therapy consisting of atomoxetine, a selective norepinephrine reuptake inhibitor (NRI), and coenzyme Q10, an antioxidant supplement. This combination has been studied for the treatment of Attention Deficit Hyperactivity Disorder (ADHD), particularly in patients who have not fully responded to atomoxetine alone. The addition of coenzyme Q10 to atomoxetine has shown improved ADHD symptoms, especially hyperactivity, impulsivity, and learning problems, with minimal additional adverse effects.

Other names
atomoxetine + ubiquinoneatomoxetine + CoQ10
02

Targets

ND1 (Mitochondrial electron transport chain complex I)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)

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