Drug intelligence / Profile preview

atorvastatin + allopurinol

Development stage
Phase 4
Lead developer
Merck Research Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

A combination of two medications used concurrently: atorvastatin, a statin medication that lowers cholesterol by inhibiting HMG-CoA reductase, and allopurinol, a xanthine oxidase inhibitor that reduces uric acid production to treat gout and prevent kidney stones. This is not a fixed-dose combination product but rather two separate medications that may be prescribed together.

02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)XO (Xanthine Oxidoreductase)

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