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Atorvastatin Teva
- Development stage
- Unknown
- Lead developer
- Teva Pharmaceutical Industries
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Atorvastatin Teva is a generic pharmaceutical product containing atorvastatin, a synthetic lipid-lowering agent belonging to the statin class. It functions as a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme responsible for the rate-limiting step in cholesterol biosynthesis. While its primary clinical use is for the treatment of hypercholesterolemia and the prevention of cardiovascular disease, Atorvastatin Teva has been specifically utilized in clinical research conducted by Region Midtjylland to evaluate its efficacy as a neoadjuvant treatment for breast cancer. This research investigates the drug's pleiotropic effects, particularly its potential to inhibit tumor cell growth and induce apoptosis by depleting mevalonate pathway intermediates necessary for protein prenylation in cancer cells.
- Brand names
- Atorvastatin Teva
- Other names
- atorvastatin
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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