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Atox1 siRNA
- Development stage
- Preclinical
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Systemic Administration Via Omv Delivery
01
Overview
Atox1 siRNA is a small interfering RNA (siRNA) designed to target and silence the expression of the Atox1 gene. Atox1 is a copper chaperone involved in cellular copper transport and has roles in cell migration and cancer progression. Silencing Atox1 can disrupt copper export mechanisms and has been explored for its potential in inducing cuproptosis (a form of cell death triggered by copper) and inhibiting tumor growth in cancer models[1][2].
- Other names
- ATOX1 siRNAATOX-1 siRNAATOX 1 siRNAAntioxidant protein 1 siRNAATOX1 small interfering RNAATOX-1 small interfering RNAATOX 1 small interfering RNAAntioxidant protein 1 small interfering RNA
02
Targets
ATOX1 (Antioxidant protein 1)
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