Drug intelligence / Profile preview

attenuated mumps vaccine

Development stage
Unknown
Lead developer
Merck
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intramuscular
01

Overview

The attenuated mumps vaccine is a live vaccine containing weakened (attenuated) forms of the mumps virus. It works by stimulating the immune system to produce antibodies and cellular immunity against the mumps virus without causing the full-blown disease, thereby providing long-term protection against mumps. The vaccine is primarily indicated for the prevention of mumps, a contagious viral infection that can cause fever, swelling of the parotid glands, and potential complications such as meningitis or orchitis. Historically, Maurice Hilleman of Merck & Co. developed the widely used Jeryl Lynn strain. While monovalent mumps vaccines like Mumpsvax were once available, the attenuated mumps vaccine is now most commonly administered as a component of combination vaccines, such as the measles, mumps, and rubella (MMR) vaccine or the measles, mumps, rubella, and varicella (MMRV) vaccine.

Brand names
Mumpsvax
Other names
mumps virus vaccine live attenuatedlive attenuated mumps vaccineJeryl Lynn strainS79 strainS-79 strainS 79 strainMuV-365 strainMuV365 strainMuV 365 strainUrabe strainL-Zagreb strainRubini strain
02

Targets

Sialoglycan (Cell-surface sialoglycan)

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