Drug intelligence / Profile preview

ATTO-1091

Development stage
Preclinical
Lead developer
Attovia Therapeutics
Modality
Trispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

ATTO-1091 is a trispecific antibody therapeutic candidate being developed by Attovia Therapeutics for the treatment of inflammatory bowel disease (IBD). It is engineered using the company's proprietary ATTOBODY™ platform, which enables the creation of multispecific biologics capable of binding to multiple epitopes or targets simultaneously with high affinity. ATTO-1091 is designed to inhibit three distinct disease-driving pathways within a single molecule to provide a more comprehensive approach to the complex immune-mediated pathology of IBD. As of early 2025, the program is in the IND-enabling phase of development.

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