Drug intelligence / Profile preview

Audistim

Development stage
Unknown
Lead developer
Mediweb - Audistimpharma
Modality
Small Molecules
Administration
Oral
01

Overview

Audistim is a multi-ingredient dietary supplement, primarily marketed as Audistim Day/Night, designed to manage chronic tinnitus and its associated impact on quality of life, sleep, and stress. The formulation is based on a multifactorial approach to tinnitus pathophysiology, incorporating ingredients that target the auditory system, microcirculation, and psychological factors. The "Day" formula typically contains Ginkgo biloba, magnesium, and B-vitamins (B3, B6, B12) to support nerve function and blood flow. The "Night" formula includes melatonin, zinc, and California poppy (Eschscholzia californica) to improve sleep quality and reduce nighttime tinnitus perception. Clinical evidence from randomized controlled trials suggests that Audistim significantly reduces the Tinnitus Handicap Inventory (THI) score, particularly in patients with permanent tinnitus.

Brand names
AudistimAudistim Day/Night
Other names
Audistim D/N
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)MTNR1A (MT1)

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