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Auto-FMP Enema
- Development stage
- Unknown
- Lead developer
- OpenBiome
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Rectal
01
Overview
Auto-FMP Enema is an autologous fecal microbiota transplantation (FMT) therapy developed by the Microbiome Health Research Institute. It is designed to prevent the colonization of antibiotic-resistant bacteria (ARB) by restoring a patient's native intestinal flora. The process involves collecting a patient's stool prior to antibiotic treatment or during a healthy state, processing it into an enema formulation, and re-administering it to the patient. This reconstitution of the microbiome aims to provide competitive exclusion against pathogens and restore colonization resistance, particularly in vulnerable populations like long-term care residents.
- Other names
- Autologous fecal microbiota transplantAutologous FMTAuto-FMP
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