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autogenous bone graft-Cairo University

Development stage
Unknown
Lead developer
Cairo University
Modality
Cell Therapies
Administration
Topical
01

Overview

Autogenous bone graft-Cairo University refers to a surgical treatment modality being evaluated as a control arm in clinical trials at Cairo University (notably NCT05445102) for the management of periodontal intrabony defects. This biologic intervention involves harvesting bone tissue from the patient's own body—specifically from the retromolar area using an automatic chip maker (ACM) bur—and processing it into particles using a hand bone mill. The graft is then implanted into periodontal defects using a modified minimally invasive surgical technique (M-MIST). As an autologous tissue, it provides a gold-standard combination of osteogenic properties (living bone-forming cells), osteoinductive properties (growth factors like bone morphogenetic proteins), and osteoconductive properties (a physical scaffold for new bone growth), aiming to regenerate lost alveolar bone and periodontal attachment in patients with periodontitis.

Other names
autogenous bone graftautologous bone graftautograft

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