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autologous αβ T cells enriched for TAA-specific clones
- Development stage
- Preclinical
- Lead developer
- BioCytics
- Modality
- Cell Therapies
- Administration
- Intravenous
01
Overview
Autologous αβ T cells enriched for TAA-specific clones is an investigational adoptive cell therapy being developed by BioCytics for the treatment of solid tumors. The therapeutic approach involves isolating a patient's own αβ T cells and selectively enriching them for clones that recognize tumor-associated antigens (TAAs) specific to the patient's malignancy. By expanding these antigen-specific T-cell populations ex vivo and reinfusing them, the therapy aims to overcome immune tolerance and mount a robust, targeted antitumor response. The program is currently in the early research or preclinical stages of development.
- Other names
- autologous αβ T cells enriched for TAA-specific clonesAutologous TAA-specific αβ T cellsAutologous reinvigorated T-cell
02
Targets
pMHC (Peptide-MHC complex family)
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