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autologous adipose stromal vascular fraction
- Development stage
- Phase 4
- Lead developer
- Arthrex
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular, Intravenous, Percutaneous, Intralesional
01
Overview
Autologous adipose stromal vascular fraction (SVF) is a heterogeneous cellular concentrate derived from a patient's own adipose tissue, typically obtained via lipoaspiration. It contains a diverse population of cells, including adipose-derived stem cells (ADSCs), mesenchymal stromal cells (MSCs), endothelial progenitor cells, pericytes, T-regulatory cells, and macrophages. SVF is utilized for its regenerative, anti-inflammatory, and immunomodulatory properties. The preparation involves enzymatic digestion or mechanical dissociation of fat tissue followed by centrifugation to isolate the cellular component from mature adipocytes. It is being investigated for a wide range of conditions, including osteoarthritis, autoimmune diseases, chronic wounds, and degenerative disorders.
- Brand names
- Lipogems
- Other names
- Adipose-derived stromal vascular fractionSVF cellsautologous SVFBiocellular regenerative therapy
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