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autologous adipose-tissue-derived mesenchymal stem cells
- Development stage
- Unknown
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous, Intraarticular, Local Injection, Surgical Implantation
01
Overview
**Autologous adipose-tissue-derived mesenchymal stem cells** are multipotent mesenchymal stromal/stem cells isolated from a patient's own adipose (fat) tissue. These cells are characterized by their capacity for self-renewal and differentiation into various cell types including adipocytes (fat cells), osteocytes (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells), neurons, and endothelial cells. They exert regenerative and therapeutic effects primarily through paracrine signaling by secreting a variety of immunomodulatory, anti-inflammatory, angiogenic, and trophic factors. Clinical and preclinical studies support their use in regenerative medicine applications for diseases such as diabetes, orthopedic conditions (cartilage and bone repair), and cardiovascular disease, among others. Autologous sourcing avoids immunogenicity issues and ethical controversies associated with embryonic or allogenic stem cells[1][2][3][4][5].
- Other names
- adipose-derived mesenchymal stem cellsadipose-derived stromal/stem cellsadipose-derived mesenchymal stromal cellsASCsADSCsAdMSCs
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