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autologous adipose tissue-derived stromal cells (Kanazawa University)
- Development stage
- Unknown
- Lead developer
- Kanazawa University
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intracoronary
01
Overview
This is an autologous cell therapy developed by Kanazawa University for the treatment of ischemic heart failure. The therapy involves the isolation of mesenchymal stem cells from a patient's own adipose tissue, which are then administered via intracoronary injection using cardiac catheterization. These adipose tissue-derived stromal cells (ADSCs) possess the potential to differentiate into cardiomyocytes, vascular endothelial cells, and vascular smooth muscle cells, thereby promoting myocardial regeneration and improving cardiac function in patients with a reduced ejection fraction (less than 40%). Adipose tissue is utilized as a source due to its relative enrichment with mesenchymal stem cells compared to bone marrow tissue.
- Other names
- ADSCsadipose tissue-derived stromal cellsadipose tissue-derived mesenchymal stem cellsautologous ADSCs
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