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autologous adipose tissue-derived stromal vascular fraction
- Development stage
- Phase 2
- Lead developer
- Dr. Himanshu Bansal Foundation
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Percutaneous Injection
01
Overview
Autologous adipose tissue-derived stromal vascular fraction (SVF) is an investigational cell therapy developed by the Dr. Himanshu Bansal Foundation for the treatment of fracture nonunion in long bones, such as the femur and tibia. The therapy involves the extraction of SVF from the patient's own adipose tissue via lipo-aspiration followed by non-enzymatic processing. This SVF contains a heterogeneous population of regenerative cells, including CD105+ and CD73+ mesenchymal stem cells (MSCs) and CD34+ hematopoietic cells. When injected percutaneously into the site of an atrophic nonunion under fluoroscopic guidance, these cells promote bone healing through their inherent osteogenic and angiogenic properties. This treatment is typically performed as an outpatient procedure and was evaluated in a retrospective study (NCT04340284).
- Other names
- autologous SVFadipose-derived stromal vascular fractionSVF
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