autologous blood injection (Isto Biologics)

**Autologous blood injection** is a patient-specific, blood-derived biologic injection therapy evaluated by Chetan M. Dojode for lateral epicondylitis. In the reported randomized trial, 2 mL of venous blood obtained from the patient's contralateral upper limb was injected at the lateral epicondyle with 1 mL of 0.5% bupivacaine used as a procedural local anesthetic. The proposed therapeutic rationale is delivery of endogenous blood and platelet-associated growth factors that may initiate a local tendon-repair cascade in degenerative tendinosis. The intervention produced slower early pain improvement than corticosteroid injection but showed superior pain outcomes at 12 weeks and 6 months in the published study. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC3626227/))

Other names

autologous bloodautologous venous blood injection