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autologous bone marrow and allogeneic umbilical cord mesenchymal stem cells + platelet-rich plasma
- Development stage
- Unknown
- Lead developer
- Van Hanh General Hospital
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
This investigational cell therapy, developed by Van Hanh General Hospital in Vietnam, is a combination treatment for type 1 diabetes mellitus. It utilizes two sources of mesenchymal stem cells (MSCs)—autologous bone marrow-derived and allogeneic umbilical cord-derived—which are administered alongside activated platelet-rich plasma (PRP). The therapy is designed to leverage the immunomodulatory and regenerative capabilities of MSCs to halt the autoimmune destruction of insulin-producing beta cells and promote the restoration of pancreatic function. It is currently being evaluated in Phase 1/2 clinical trials (NCT04061746).
- Other names
- MSC and PRPMSC transplantation for Type 1 Diabetes Mellitusmesenchymal stem cells-Van Hanh General Hospital-type 1 diabetes mellitus
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