Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
autologous bone marrow-derived mesenchymal stem cells (Mashhad University of Medical Sciences)
- Development stage
- Unknown
- Lead developer
- Mashhad University of Medical Sciences
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
This autologous bone marrow-derived mesenchymal stem cell (BM-MSC) therapy is an investigational biologic developed by Mashhad University of Medical Sciences for the treatment of refractory rheumatoid arthritis. The therapy involves harvesting multipotent stromal cells from the patient's own bone marrow, expanding them in vitro under sterile conditions, and re-administering them as a single intravenous infusion. These cells possess potent immunomodulatory and anti-inflammatory properties, exerting their therapeutic effect by modulating T cell responses, increasing the population of regulatory T cells (Tregs), and suppressing the production of pro-inflammatory cytokines. The therapy is specifically targeted at patients who have shown inadequate responses to conventional non-biological disease-modifying antirheumatic drugs (DMARDs).
- Other names
- autologous BM-MSCsautologous mesenchymal stem cellsBM-MSCs (MUMS)
Beyond the preview
Go deeper on autologous bone marrow-derived mesenchymal stem cells (Mashhad University of Medical Sciences).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on autologous bone marrow-derived mesenchymal stem cells (Mashhad University of Medical Sciences).