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autologous bone marrow-derived mesenchymal stem cells (University Hospitals Cleveland Medical Center)
- Development stage
- Unknown
- Lead developer
- University Hospitals Cleveland Medical Center
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intradiscal
01
Overview
This investigational cell therapy, developed by University Hospitals Cleveland Medical Center, utilizes autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) for the treatment of symptomatic intervertebral disc degeneration. The procedure involves harvesting the patient's own bone marrow, expanding the MSCs in culture, and then re-injecting them percutaneously under image guidance directly into the nucleus pulposus of the affected disc. The therapy aims to facilitate disc repair and regeneration, potentially alleviating chronic low back pain in patients who have not responded to conservative treatments.
- Other names
- Autologous MSCs for Degenerated Disc DiseaseAutologous BM-MSCs
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