Drug intelligence / Profile preview

autologous bone marrow-derived mesenchymal stromal cells + platelet lysate (Royan Institute)

Development stage: Unknown
Lead developer: Royan Institute
Modality: Stem Cell Therapies → Cell Therapies
Administration: Percutaneous, Implant

Overview

The intervention referred to as 'percutaneous injection' in this context is an autologous cell therapy product combining bone marrow-derived mesenchymal stromal/stem cells (BM-MSCs) with platelet lysate (PL). Developed by the Royan Institute for Stem Cell Biology and Technology, this combination is designed to treat long bone nonunion, specifically tibia nonunion, by leveraging the osteogenic and regenerative properties of MSCs. The platelet lysate acts as a growth-factor-rich supplement and carrier, enhancing the local environment for bone healing. The treatment is administered via percutaneous implantation directly into the site of the nonunion.

Brand names: Provacel
Other names: percutaneous injectionautologous BM-MSCs + PLBM-MSC + platelet lysate

Beyond the preview

Go deeper on autologous bone marrow-derived mesenchymal stromal cells + platelet lysate (Royan Institute).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on autologous bone marrow-derived mesenchymal stromal cells + platelet lysate (Royan Institute).

Explore the full profile