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autologous bone marrow mononuclear cells + umbilical cord-derived mesenchymal stem cells
- Development stage
- Preclinical
- Lead developer
- ReeLabs
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Injection
01
Overview
This therapy is a **combination stem cell therapy** being developed by **ReeLabs** for **Duchenne Muscular Dystrophy**. It combines **autologous bone marrow mononuclear cells** with **allogeneic umbilical cord-derived mesenchymal stem cells** and was described in an Indian clinical program in which patients received one session of autologous BM-MNCs followed by three sessions of UC-MSCs. The therapeutic rationale is to pair the regenerative and trophic paracrine activity of bone marrow mononuclear cells with the immunomodulatory, anti-inflammatory, and tissue-repair properties of umbilical cord-derived mesenchymal stem cells in an effort to support muscle regeneration and functional stabilization in dystrophin-deficient muscle. No discrete molecular target, brand name, or standard development code appears to have been assigned.
- Other names
- autologous BM-MNCs + UC-MSCscombination stem cell therapyautologous bone marrow-derived mononuclear cells + umbilical cord-derived mesenchymal stem cells
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