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autologous bone marrow progenitor cells
- Development stage
- Phase 1
- Lead developer
- Aryn Knight
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Autologous bone marrow progenitor cells (BMPC) are a cell therapy product derived from a patient's own bone marrow. The treatment involves harvesting bone marrow, processing it to isolate progenitor cells, and re-administering them to the patient. In the context of spinal cord injury (SCI), these cells are hypothesized to promote recovery through the secretion of neurotrophic factors, modulation of the inflammatory response, and potential support of endogenous repair mechanisms. This specific intervention is being evaluated in a Phase 1 clinical trial led by Aryn Knight for safety and efficacy in pediatric patients with spinal cord injury, where the cells are administered via intravenous infusion.
- Other names
- l-Aryn Knight-spinal cord injuryautologous bone marrow cell transplantationautologous bone marrow-derived mononuclear cells
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