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autologous conjunctival epithelial stem cells
- Development stage
- Unknown
- Lead developer
- Eye Institute of Xiamen University
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Ophthalmic, Implant
01
Overview
Autologous conjunctival epithelial stem cells are a cell therapy product involving the harvest, ex vivo expansion, and subsequent transplantation of a patient's own conjunctival stem cells. This approach is primarily used for ocular surface reconstruction in patients with conditions like limbal epithelial stem cell deficiency (LSCD), symblepharon, and conjunctival fornix cicatrization. By expanding these cells in a laboratory setting, typically on a carrier such as amniotic membrane, clinicians can generate a sufficient quantity of healthy epithelial tissue to restore the ocular surface, particularly when the limbus is severely damaged or when conjunctival tissue is lost due to scarring or chemical burns. The Eye Institute of Xiamen University has been a key developer in evaluating this therapy in clinical trials.
- Other names
- autologous conjunctival epithelial stem cell therapyex vivo expanded autologous conjunctival epithelial stem cells
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