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autologous fibrin glue
- Development stage
- Phase 1
- Lead developer
- Inonu University
- Modality
- Peripheral Blood HSCs → Hematopoietic Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies
- Administration
- Topical
01
Overview
Autologous fibrin glue is a patient-specific, blood-derived platelet-concentrate preparation investigated by Inonu University for management of palatal donor-site wounds after free gingival graft surgery. The preparation is produced from the patient's own blood and applied to the palatal wound as an adhesive fibrin-rich biologic matrix. It is intended to support hemostasis and tissue repair through the local fibrin scaffold and platelet-derived mediators that may promote fibroblast activity and angiogenesis. In a randomized controlled clinical trial, autologous fibrin glue improved wound-healing and postoperative morbidity measures versus control treatment and showed superior wound-healing measures to injectable platelet-rich fibrin in this setting. ([link.springer.com](https://link.springer.com/article/10.1007/s00784-020-03320-6))
- Other names
- AFGautologue fibrin glue
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