autologous growth factor eye drops

Autologous growth factor eye drops are a personalized biological therapy derived from a patient's own peripheral blood, specifically processed to concentrate essential proteins and growth factors that facilitate ocular surface healing. Developed by the Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau, this treatment is primarily investigated for the management of pterygium, particularly as an adjuvant therapy following surgical excision. The preparation involves the isolation of plasma rich in growth factors (PRGF), which contains a cocktail of bioactive molecules including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-beta), epidermal growth factor (EGF), and fibroblast growth factor (FGF). These factors act synergistically to promote epithelial cell proliferation, migration, and differentiation while modulating the inflammatory environment of the ocular surface. By mimicking the natural composition of tears and providing a concentrated source of regenerative signals, these eye drops aim to accelerate post-operative recovery and reduce the high recurrence rates associated with pterygium surgery.

Other names

Plasma Rich in Growth Factors eye dropsPRGF eye dropsautologous serum eye dropsE-PRGF