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Autologous human umbilical cord blood (hUCB) cell therapy involves the intravenous infusion of a patient's own cord blood, which was harvested and cryopreserved at birth. In the context of perinatal arterial ischemic stroke (AIS), this therapy is being evaluated for its safety and potential to improve functional outcomes in children. The cells are hypothesized to migrate to the site of neonatal brain injury and facilitate repair through the release of anti-inflammatory cytokines and neurotrophic factors, thereby reducing secondary neuronal loss and promoting neuroplasticity. This specific research is led by Aryn Knight at the University of Texas Health Science Center at Houston.
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