autologous nucleus pulposus cell transplantation

Autologous nucleus pulposus cell transplantation is an autologous cell therapy being investigated for the treatment of lumbar intervertebral disc herniation. The procedure involves harvesting nucleus pulposus cells from a patient's herniated disc material during a primary surgical excision, followed by the re-implantation of these cells back into the disc space. The goal is to regenerate the disc's structural integrity and biological function by replenishing the cell population responsible for maintaining the extracellular matrix. This specific program was evaluated in a clinical study at the Navy General Hospital in China.