Drug intelligence / Profile preview

autologous platelet gel (National Healing Corporation)

Development stage
Preclinical
Lead developer
Cytomedix
Modality
Peripheral Blood HSCs → Hematopoietic Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies
Administration
Topical
01

Overview

Autologous platelet gel is an investigational topical, autologous blood-derived biologic developed by National Healing Corporation for lower-extremity chronic venous insufficiency ulcers. The point-of-care product combines a patient-derived autologous platelet concentrate with topical thrombin to generate a platelet gel applied directly to the ulcer in addition to standard venous-ulcer care. Platelets provide a localized mixture of wound-healing growth factors, cytokines, and matrix-associated mediators intended to support granulation tissue formation, angiogenesis, re-epithelialization, and tissue repair. It was evaluated in the multicenter randomized study NCT00273234. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00273234))

Other names
Autologous Platelet GelAPG

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