Drug intelligence / Profile preview

autologous platelet growth factor

Development stage
Unknown
Lead developer
Ruijin Hospital
Administration
Intradermal, Percutaneous
01

Overview

Autologous platelet growth factor is a biologic preparation derived from a patient's own blood, specifically processed to concentrate growth factors released from activated platelets. These factors, including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and transforming growth factor-beta (TGF-β), are essential for tissue regeneration, angiogenesis, and cellular proliferation. In the context of androgenetic alopecia, this therapy is administered via local scalp injections to stimulate hair follicle activity and improve hair density. A specific mechanized freeze-dried formulation developed by Ruijin Hospital aims to provide a more stable and standardized alternative to traditional liquid autologous preparations like Concentrated Growth Factors (CGF).

Other names
autologous platelet growth factormechanized freeze-dried autologous platelet growth factorfreeze-dried autologous platelet growth factor
02

Targets

TGFBR (TGF-beta receptor)PDGFR (PDGFR family)IGF-1R (Insulin-like growth factor 1 receptor)EGFR T790M (Epidermal growth factor receptor T790M mutant)VEGFR (VEGFR family)

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