Drug intelligence / Profile preview

autologous platelet-rich plasma eye drops (Assiut University)

Development stage
Unknown
Lead developer
Assiut University
Administration
Ophthalmic
01

Overview

Autologous platelet-rich plasma (PRP) eye drops are a biologic therapy derived from a patient's own peripheral blood, currently being evaluated by Assiut University for the treatment of persistent corneal epithelial defects and dry eye disease. The preparation involves centrifuging whole blood to obtain a concentrated platelet fraction, which is then diluted for ophthalmic use. PRP contains a high concentration of epitheliotrophic growth factors, including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and epidermal growth factor (EGF). These factors promote the proliferation, migration, and differentiation of corneal epithelial cells, facilitating wound healing and the regeneration of the ocular surface in various pathological conditions.

Other names
PRP eye dropsautologous PRP eye dropsplatelet-rich plasma eye drops
02

Targets

EGFR (Epidermal growth factor receptor)PDGFR (PDGFR family)TGFBR (TGF-beta receptor)

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