Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
autologous salivary gland stem cells
- Development stage
- Unknown
- Lead developer
- University Medical Center Groningen
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraglandular
01
Overview
Autologous salivary gland stem cells are an experimental cell therapy developed by the Universitair Medisch Centrum Groningen (UMCG) for the treatment of xerostomia (dry mouth) and salivary gland hypofunction, typically resulting from radiotherapy for head and neck cancer. The procedure involves harvesting a small biopsy of the patient's salivary gland tissue prior to radiation treatment. Stem and progenitor cells (often characterized by markers like c-Kit or CD117) are isolated, expanded in vitro, and subsequently transplanted back into the patient's damaged salivary glands. The mechanism of action relies on the ability of these stem cells to differentiate into functional acinar cells and provide paracrine support, thereby regenerating the secretory tissue and restoring saliva production.
- Other names
- SaliStemautologous salivary gland-derived stem cellssalivary gland stem/progenitor cells
Beyond the preview
Go deeper on autologous salivary gland stem cells.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on autologous salivary gland stem cells.