autologous umbilical cord blood transfusion

Autologous umbilical cord blood transfusion is a biological therapy involving the collection of a neonate's own umbilical cord blood at birth, followed by its processing and re-infusion. In the specific protocol led by Sahar M.A. Hassanein, the intervention is targeted at preterm neonates (<35 weeks gestation) and low birth weight infants (<1500g). The procedure involves separating the mononuclear cell layer for immediate transfusion (within 6 hours) and storing the red blood cell component for later transfusion to maintain hemoglobin levels above 10 g/dL. This approach is designed to treat and prevent complications of prematurity, including anemia of prematurity, respiratory distress syndrome (RDS), and intraventricular hemorrhage (IVH), by providing a rich source of autologous hematopoietic stem cells and red blood cells, thereby reducing the risks associated with allogeneic blood transfusions.

Other names

autologous cord blood transfusionautologous umbilical cord bloodAUCB transfusion