autumn crocus extract

Autumn crocus extract is a botanical preparation derived from the plant *Colchicum autumnale*. Its primary active constituent is the alkaloid colchicine, which exerts potent anti-inflammatory effects by binding to tubulin and inhibiting microtubule polymerization. This action disrupts leucocyte chemotaxis, degranulation, and phagocytosis. In the context of cardiovascular medicine, researchers at Gentofte Hospital and other institutions have investigated the use of colchicine-containing preparations for the prevention and treatment of atrial fibrillation and atrial flutter, particularly following cardiac surgery. The rationale is that by mitigating the local and systemic inflammatory response associated with surgical trauma or underlying cardiac conditions, the extract can reduce the incidence of arrhythmia.

Brand names

ColchysatColchysat Bürger

Other names

Colchicum autumnale extractMeadow saffron extractColchicum extractcolchicine