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Avanz Mite mix
- Development stage
- Unknown
- Lead developer
- ALK Abelló
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
Avanz Mite mix is a subcutaneous immunotherapy (SCIT) product developed by ALK-Abelló for the treatment of allergic rhinitis and associated asthma caused by house dust mites. It contains biological extracts from the two major house dust mite species, *Dermatophagoides pteronyssinus* and *Dermatophagoides farinae*, formulated with an aluminum hydroxide adjuvant. The vaccine works by modulating the immune system, specifically by inducing the production of allergen-specific IgG4 antibodies and reducing immediate skin reactivity and IgE-mediated responses. This shift in the immune profile helps desensitize patients to the allergens, thereby reducing symptoms of perennial allergic rhinitis and potentially preventing the progression to asthma.
- Brand names
- Avanz Mite mixAVANZ MITE
- Other names
- Dermatophagoides mix immunotherapyHouse dust mite allergen extractAVANZ Mite mix-ALK-Abelló
02
Targets
Der f-specific IgE (Dermatophagoides farinae-specific IgE)Dermatophagoides pteronyssinus major allergens-specific IgE/immune recognition
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