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AVB-006 is a discontinued allogeneic encapsulated cell therapy developed by Avenge Bio using the proprietary LOCOcyte™ platform. The LOCOcyte™ technology involves the local administration of engineered, encapsulated cells designed to provide sustained, high-concentration delivery of therapeutic payloads directly to the tumor microenvironment. This approach aims to maximize the therapeutic effect of potent immune-modulators while minimizing systemic exposure and associated toxicities. Although the specific payload for AVB-006 was not publicly disclosed, the platform generally focuses on immunomodulatory proteins for the treatment of solid tumors.
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