Drug intelligence / Profile preview

avian flu vaccine

Development stage
Unknown
Lead developer
Youfeng Biotechnology
Modality
Peptides, Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intratracheal, Conjunctival, In Ovo, Intramuscular, Intradermal
01

Overview

Avian flu vaccine is an investigational peptide-based vaccine candidate developed by Youfeng Biotechnology for the prevention of H5N1 avian influenza. The vaccine utilizes the proprietary Ii-Key peptide technology platform, which involves modifying antigenic peptides by linking them to a specific segment of the MHC class II-associated invariant chain (the Ii-Key peptide). This modification facilitates the direct loading of H5N1-specific epitopes into the MHC class II binding groove of antigen-presenting cells, bypassing the traditional intracellular processing pathway. This mechanism is designed to significantly enhance the presentation of antigens to CD4+ T-helper cells, thereby inducing a robust and protective T-cell immune response against the H5N1 virus. The candidate has completed Phase 1 clinical development.

Other names
Avian flu vaccineH5N1 peptide vaccineH-5N1 peptide vaccineH 5N1 peptide vaccineavian influenza vaccine
02

Targets

HA (Hemagglutinin)M1 (Muscarinic acetylcholine receptor M1)Neuraminidase

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