Drug intelligence / Profile preview

Aviga

Development stage
Phase 1
Lead developer
NatiVita
Modality
Small Molecules
Administration
Oral
01

Overview

Aviga is a pharmaceutical drug manufactured by JLLC NATIVITA, Republic of Belarus. It is a generic version of Sutent, containing 50 mg of Sunitinib. Sunitinib is a small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor. It works by inhibiting various RTKs, including all receptors for platelet-derived growth factor (PDGF-Rs), vascular endothelial growth factor receptors (VEGFRs), c-KIT (CD117), RET, and FLT3. This inhibition reduces tumor vascularization, impedes tumor growth and angiogenesis, and promotes cancer cell apoptosis.

Brand names
Aviga
02

Targets

KIT (c-KIT proto-oncogene receptor tyrosine kinase)PDGFR (PDGFR family)RET (Rearranged during transfection receptor tyrosine kinase)FLT3 (Fms related receptor tyrosine kinase 3)VEGFR (VEGFR family)

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