Drug intelligence / Profile preview

AVIM + Virtue SAB

Development stage: Unknown
Lead developer: Orchestra BioMed
Modality: Small Molecules
Administration: Intravascular, Intracardiac

Overview

AVIM + Virtue SAB refers to the two lead product candidates from Orchestra BioMed: Atrioventricular Interval Modulation (AVIM) Therapy and the Virtue Sirolimus AngioInfusion Balloon (Virtue SAB). AVIM Therapy is a bioelectronic treatment delivered via a standard pacemaker, designed to achieve immediate and sustained blood pressure reduction in patients with hypertensive heart disease by modulating the atrioventricular interval. Virtue SAB is a first-of-its-kind, non-coated drug delivery angioplasty balloon system that delivers a proprietary extended-release liquid formulation of sirolimus (SirolimusEFR) directly into the vessel wall for the treatment of atherosclerotic artery disease, including coronary in-stent restenosis, small vessel disease, and peripheral artery disease.

Other names: AVIM TherapyVirtue Sirolimus AngioInfusion BalloonSirolimusEFR

Targets

FKBP1AMechanistic target of rapamycin complex 1

Beyond the preview

Go deeper on AVIM + Virtue SAB.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on AVIM + Virtue SAB.

Explore the full profile