Drug intelligence / Profile preview

Avita HP

Development stage
Unknown
Lead developer
Ozone Pharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

Avita HP is a topical triple-combination pharmaceutical cream primarily indicated for the short-term treatment of moderate-to-severe melasma of the face. It contains three active ingredients that work synergistically to address hyperpigmentation: hydroquinone, tretinoin, and mometasone furoate. Hydroquinone acts as a depigmenting agent by inhibiting the enzyme tyrosinase, which is essential for melanin synthesis. Tretinoin, a retinoid, promotes epidermal cell turnover and the shedding of pigmented keratinocytes, while also enhancing the penetration of hydroquinone into the skin. Mometasone furoate is a medium-potency corticosteroid that provides anti-inflammatory and antipruritic effects, helping to mitigate the skin irritation and erythema frequently caused by the other two components. This combination is designed to provide superior efficacy in skin lightening compared to the individual components while managing local tolerability.

Brand names
Avita HP
Other names
Hydroquinone + Tretinoin + Mometasone Furoate
02

Targets

RARA (Retinoic acid receptor alpha)TYR (Tyrosinase)RARB (Retinoic acid receptor beta)GR (Glucocorticoid receptor)RARG (Retinoic acid receptor gamma)

Beyond the preview

Go deeper on Avita HP.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Avita HP.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call