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axillary microbial transplantation
- Development stage
- Unknown
- Lead developer
- Ghent University
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Topical
01
Overview
Axillary microbial transplantation is an experimental microbiome-based therapy developed by researchers at Ghent University, led by Dr. Chris Callewaert, for the treatment of bromhidrosis (excessive body odor). The procedure involves the transfer of a healthy microbial community from the armpit of a non-malodorous donor to a recipient whose axillary microbiome is dominated by odor-producing bacteria, primarily *Corynebacterium* species. By introducing commensal bacteria such as *Staphylococcus hominis* and *Staphylococcus epidermidis*, the transplant aims to shift the microbial composition toward a non-odor-producing state. Clinical evaluations have demonstrated high short-term success rates in reducing malodor by altering the metabolic activity of the axillary skin flora.
- Other names
- Microbial community transplantationArmpit transplantAxillary microbiota transplantationMicrobial transplant
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