Drug intelligence / Profile preview

Axio

Development stage
Unknown
Lead developer
LifeVantage
Modality
Small Molecules
Administration
Oral
01

Overview

Axio is a multi-ingredient dietary supplement developed by LifeVantage, marketed as a "smart energy" or nootropic drink mix designed to enhance mental focus, clarity, and mood. The product is formulated with a blend of bioactive ingredients, including caffeine (in the regular version), B vitamins (B3, B6, B12), magnesium, and botanical extracts such as green tea, pine bark, and quercetin. Its mechanism of action is multifaceted: caffeine acts as an adenosine receptor antagonist to increase alertness and reduce fatigue; L-theanine modulates neurotransmitters like glutamate and GABA to promote a state of relaxed alertness; and botanical antioxidants provide neuroprotective effects by mitigating oxidative stress. Axio is often positioned within the "biohacking" community as a cognitive enhancer that provides sustained energy without the "crash" associated with traditional high-sugar energy drinks.

Brand names
AxioAxio RegularAxio Decaf
Other names
LifeVantage AxioAxio Smart Energy
02

Targets

ADORA2A (Adenosine A₂A Receptor)GluR (Glutamate receptors)ADORA1 (Adenosine receptor A1 subtype)

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