Drug intelligence / Profile preview

axulin

Development stage
Phase 2
Lead developer
Housey Pharmaceutical Research Laboratories
Modality
Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

Axulin is a **plant-based natural health product** formulated as a mixture of botanical extracts, specifically those present in edible herbs and vegetables, identified through screening over 100,000 compounds[1][7][10]. The **active ingredient**—designated as HP-211—targets the IRS-2 branch of the insulin signaling pathway, **enhancing insulin-mediated glucose uptake** into cells and thereby supporting healthy blood sugar metabolism[1][7]. Laboratory and early clinical studies show HP-211 can **increase cellular glucose uptake** and decrease circulating blood glucose and triglyceride levels, with benefits in **insulin resistance, prediabetes, metabolic syndrome, and type II diabetes**[1][4][5][7][10]. Developed after years of research by Housey Pharma, Axulin is marketed as a nutritional support supplement and is **approved by Health Canada as a Natural Health Product** (NPN #80050544)[4][7].

Brand names
Axulin
Other names
HP-211HP211HP 211
02

Targets

IRS2 (Insulin receptor substrate 2)

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