azatadine

Azatadine is a first-generation antihistamine and anticholinergic drug that was originally synthesized in 1963 by Schering-Plough. It acts as an H1 receptor antagonist, blocking the effects of histamine at H1-receptor sites on effector cells. This reduces the intensity of allergic reactions and tissue injury responses involving histamine release. Azatadine is used to treat symptoms associated with allergies and the common cold such as sneezing, runny nose, itching, watery eyes, hives, rashes, and eustachian tube congestion. It also exhibits anti-serotonin and anticholinergic (drying) effects[1][2][3][5].

Brand names

OptimineIdulianZadine

Other names

azatadine maleateazatadine dimaleate6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyridine dimaleate